Homology Modeling of Leishmanolysin (gp63) from Leishmania panamensis and Molecular Docking of Flavonoids
نویسندگان
چکیده
منابع مشابه
Leishmania panamensis: a 44bp deletion in gp63 gene is found in cDNA and genomic libraries.
Leishmanolysin (EC 3.4.24.36) (gp63) is a zinc metalloprotease (ND Rawlings et al. 1995 Methods Enzymol 248: 183-228) abundantly expressed in the promastigote form of Leishmania parasites, where it is attached to the plasma membrane by a glycosylphosphatidylinositol (GPI) anchor (P Schneider et al. It has been suggested that gp63 becomes active at multiple steps during the process of macrophage...
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ژورنال
عنوان ژورنال: ACS Omega
سال: 2020
ISSN: 2470-1343,2470-1343
DOI: 10.1021/acsomega.0c01584